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Map3k11m1J
Spontaneous Allele Detail
Nomenclature
Symbol: Map3k11m1J
Name: mitogen-activated protein kinase kinase kinase 11; mutation 1 Jackson
MGI ID: MGI:4999723
Synonyms: bloodline
Gene: Map3k11  Location: Chr19:5738770-5752893 bp, + strand  Genetic Position: Chr19, 4.34 cM
Red dorsal lines in the skin of Map3k11m1J/Map3k11m1J pups (right and center) compared to control (left)

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  STOCK Bdnftm3Jae/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA spontaneous G-to-A mutation at position 5,695,295 (GRCm38) changes amino acid 293 from glutamate to lysine (p.E293K). (J:175214, J:176116)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Map3k11 Mutation:  24 strains or lines available
References
Original:  J:175214 Karst SY, et al., A spontaneous point mutation in the Map3k11 gene causes dorsal stripes and necrotic tooth pulp. MGI Direct Data Submission. 2011;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory