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Adgrl3Gt(S17-5H1)Sor
Gene trapped Allele Detail
Nomenclature
Symbol: Adgrl3Gt(S17-5H1)Sor
Name: adhesion G protein-coupled receptor L3; gene trap S17-5H1, Philippe Soriano
MGI ID: MGI:4973916
Gene: Adgrl3  Location: Chr5:81020138-81825133 bp, + strand  Genetic Position: Chr5, 42.62 cM
Mutation
origin
Mutant Cell Line:  S17-5H1
Germline Transmission:  Earliest citation of germline transmission: J:185872
Parent Cell Line:  AK7.1 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: ROSAFARY
 
Mutation detailsTrapped gene association determined by genome coordinate overlap and strand. RT-PCR confirmed the absence of transcript expression. (J:185872)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgrl3 Mutation:  55 strains or lines available
Notes
While genetic variation does not include ADGR13 null mutations in humans, null mice display some phenotypes reminiscent of ADHD and can be utilized as a working model to better understand the function in disease (J:259247).
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory