Hsd11b2^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Hsd11b2^{tm1(KOMP)Vlcg}
• Name: hydroxysteroid 11-beta dehydrogenase 2; targeted mutation 1, Velocigene
• MGI ID: MGI:4951301
• Gene: Hsd11b2 Location: Chr8:106245387-106250620 bp, + strand Genetic Position: Chr8, 53.04 cM
• IMPC: Hsd11b2 gene page

Mutation origin

• Mutant Cell Lines: 16141A-A11, 16141A-D9, 16141A-D12, 16141A-F9, 16141A-G4, 16141A-H5
• Germline Transmission: Unknown
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 4601bp between positions 106245500-106250100 of Chromosome 8 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Hsd11b2 Mutation: 19 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 1 reference(s)