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Col1a1tm5(tetO-GFP/RNAi:Cdkn2a)Slowe
Targeted Allele Detail
Nomenclature
Symbol: Col1a1tm5(tetO-GFP/RNAi:Cdkn2a)Slowe
Name: collagen, type I, alpha 1; targeted mutation 5, Scott Lowe
MGI ID: MGI:4950584
Synonyms: TG-p19.157
Gene: Col1a1  Location: Chr11:94936224-94953042 bp, + strand  Genetic Position: Chr11, 59.01 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171191
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Inducible, Knockdown, RMCE-ready, Reporter)
Mutation:    Insertion
 
Mutation detailsRMCE on KH2 cells inserted a cassette that contains the tetracycline promoter and a GFP fusion with an Mir30e-based short hairpin sequence targeting Cdkn2a (TG-p19.157) into the 3'UTR. (J:171191)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a1 Mutation:  68 strains or lines available
Notes
The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae.

References
Original:  J:171191 Premsrirut PK, et al., A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell. 2011 Apr 1;145(1):145-58
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory