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Targeted Allele Detail
Symbol: Abi1tm1.2Lko
Name: abl-interactor 1; targeted mutation 1.2, Leszek Kotula
MGI ID: MGI:4950558
Gene: Abi1  Location: Chr2:22940073-23040241 bp, - strand  Genetic Position: Chr2, 15.18 cM
Germline Transmission:  Earliest citation of germline transmission: J:171342
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA single loxP site was inserted 5' of exon 1 and a floxed and FRT flanked neo cassette was inserted 3' of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. Cre mediated recombination removed exon 1. (J:171342)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abi1 Mutation:  67 strains or lines available
Original:  J:171342 Dubielecka PM, et al., Essential role for Abi1 in embryonic survival and WAVE2 complex integrity. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7022-7
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.06
The Jackson Laboratory