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Targeted Allele Detail
Symbol: Cd151tm2Nki
Name: CD151 antigen; targeted mutation 2, The Netherlands Cancer Institute
MGI ID: MGI:4950443
Synonyms: Cd151fl, Cd151tm2Son
Gene: Cd151  Location: Chr7:141467392-141471473 bp, + strand  Genetic Position: Chr7, 86.82 cM
Germline Transmission:  Earliest citation of germline transmission: J:205736
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. This allele was used to generate Cd151tm1Nki. (J:114988)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd151 Mutation:  33 strains or lines available
Original:  J:114988 Sachs N, et al., Kidney failure in mice lacking the tetraspanin CD151. J Cell Biol. 2006 Oct 9;175(1):33-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory