Tktl1^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Tktl1^tm1Arte
• Name: transketolase-like 1; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:4949665
• Gene: Tktl1 Location: ChrX:73220865-73252104 bp, + strand Genetic Position: ChrX, 37.83 cM
• Alliance: Tktl1^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171154
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 4 through 7 were deleted. (J:171154)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tktl1 Mutation: 9 strains or lines available

References

• Original: J:171154 Bentz S, et al., Lack of transketolase-like (TKTL) 1 aggravates murine experimental colitis. Am J Physiol Gastrointest Liver Physiol. 2011 Apr;300(4):G598-607
• All: 1 reference(s)