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Slc19a3tm1Said
Targeted Allele Detail
Nomenclature
Symbol: Slc19a3tm1Said
Name: solute carrier family 19, member 3; targeted mutation 1, Hamid M Said
MGI ID: MGI:4948864
Synonyms: Slc19a3tm1Igl, Slc19a3tm1Itl
Gene: Slc19a3  Location: Chr1:83012523-83038448 bp, - strand  Genetic Position: Chr1, 42.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170952
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 1 and 2. The absence of protein expression was confirmed by western blot analysis on intestine extracts. (J:170952)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc19a3 Mutation:  4 strains or lines available
References
Original:  J:170952 Reidling JC, et al., Impaired intestinal vitamin B1 (thiamin) uptake in thiamin transporter-2-deficient mice. Gastroenterology. 2010 May;138(5):1802-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory