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Map1stm1.1Lliu
Targeted Allele Detail
Nomenclature
Symbol: Map1stm1.1Lliu
Name: microtubule-associated protein 1S; targeted mutation 1.1, Leyuan Liu
MGI ID: MGI:4948361
Gene: Map1s  Location: Chr8:71358618-71370173 bp, + strand  Genetic Position: Chr8, 34.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170757
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exons 4 and 5. The absence of protein expression was confirmed by western blot analysis on heart extracts. (J:170757)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map1s Mutation:  24 strains or lines available
References
Original:  J:170757 Xie R, et al., Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation. J Biol Chem. 2011 Mar 25;286(12):10367-77
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory