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Cdc14btm1.2Pzg
Targeted Allele Detail
Nomenclature
Symbol: Cdc14btm1.2Pzg
Name: CDC14 cell division cycle 14B; targeted mutation 1.2, Pumin Zhang
MGI ID: MGI:4948253
Synonyms: Cdc14bdeltaE2
Gene: Cdc14b  Location: Chr13:64192545-64274973 bp, - strand  Genetic Position: Chr13, 33.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170763
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exon 2 and the neo cassette. RT-PCR confirmed the expression of two truncated transcripts that are not predicted to produce a functional protein. (J:170763)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdc14b Mutation:  19 strains or lines available
References
Original:  J:170763 Wei Z, et al., Early-onset aging and defective DNA damage response in cdc14b-deficient mice. Mol Cell Biol. 2011 Apr;31(7):1470-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory