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Crptm1Hjf
Targeted Allele Detail
Nomenclature
Symbol: Crptm1Hjf
Name: C-reactive protein, pentraxin-related; targeted mutation 1, H J Fehling
MGI ID: MGI:4947397
Gene: Crp  Location: Chr1:172698055-172833031 bp, + strand  Genetic Position: Chr1, 80.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170409
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced coding sequence in exon 1 and most of exon 2. The absence of protein expression was confirmed by western blot anaylsis on serum. (J:170409)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crp Mutation:  7 strains or lines available
References
Original:  J:170409 Teupser D, et al., No reduction of atherosclerosis in C-reactive protein (CRP)-deficient mice. J Biol Chem. 2011 Feb 25;286(8):6272-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory