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Del(2Cd59b-Cd59a)1Jha
Targeted Allele Detail
Nomenclature
Symbol: Del(2Cd59b-Cd59a)1Jha
Name: deletion, Chr 2, Jose A Halperin 1
MGI ID: MGI:4947111
Synonyms: Cd59a/Cd59btm1Jha, mCd59ab-
Gene: Del(2Cd59b-Cd59a)1Jha  Location: unknown  Genetic Position: Chr2, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:170754
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
  Del(2Cd59b-Cd59a)1Jha involves 2 genes/genome features (Cd59b, Cd59a) View all
 
Mutation detailsA neo cassette replaced exons 1 and 2 of Cd59a and exon 4 of Cd59b. The absence of either protein was confirmed by FACS analysis on platelets. (J:170754)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(2Cd59b-Cd59a)1Jha Mutation:  0 strains or lines available
References
Original:  J:170754 Qin X, et al., Generation and phenotyping of mCd59a and mCd59b double-knockout mice. Am J Hematol. 2009 Feb;84(2):65-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory