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Rsad2tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Rsad2tm1Aki
Name: radical S-adenosyl methionine domain containing 2; targeted mutation 1, Shizuo Akira
MGI ID: MGI:4943550
Gene: Rsad2  Location: Chr12:26442753-26456452 bp, - strand  Genetic Position: Chr12, 9.69 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169840
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 1 and 2. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts treated with IFNbeta. (J:169840)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rsad2 Mutation:  10 strains or lines available
References
Original:  J:169840 Saitoh T, et al., Antiviral Protein Viperin Promotes Toll-like Receptor 7- and Toll-like Receptor 9-Mediated Type I Interferon Production in Plasmacytoid Dendritic Cells. Immunity. 2011 Mar 25;34(3):352-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory