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Tg(Prnp-SNCA*A53T)25Mkle
Transgene Detail
Nomenclature
Symbol: Tg(Prnp-SNCA*A53T)25Mkle
Name: transgene insertion 25, Michael K Lee
MGI ID: MGI:4942280
Synonyms: N2-5
Transgene: Tg(Prnp-SNCA*A53T)25Mkle  Location: unknown  
Transgene
origin
Strain of Origin:  (C3H/HeJ x C57BL/6J)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:77344 Lee MK, et al., Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8968-73
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory