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Transposon induced Allele Detail
Symbol: Smoc1Tn(sb-lacZ,GFP)IR3.1Jtak
Name: SPARC related modular calcium binding 1; transposon insertion IR3.1, Junji Takeda
MGI ID: MGI:4941776
Synonyms: PV384, Smoc1TgTn(sb-lacZ,GFP)IR3.1Jtak, Smoc1Tp
Gene: Smoc1  Location: Chr12:81026808-81186414 bp, + strand  Genetic Position: Chr12, 37.28 cM
Strain of Origin:  mixed
Allele Type:    Transposon induced
Mutation:    Transposon insertion
Mutation detailsA single copy of the gene trap vector inserted into intron 1. The vector consists of the inverted repeat direct repeat sequence specific for sleeping beauty transposase flanking human BCL2 splice acceptor sequence, IRES, lacZ, poly A signal, a chimeric CAG promoter containing sequence from the chicken ACTB promoter, GFP, and splice donor sequence. This allele was generated from mice carrying TgTn(sb-lacZ,GFP)IR3Jtak and Tg(CAG-sb10)1Jtak. The absence of native transcript was confirmed by RT-PCR. (J:104043)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Smoc1 Mutation:  19 strains or lines available
Original:  J:104043 Keng VW, et al., Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system. Nat Methods. 2005 Oct;2(10):763-9
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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