Slc6a8^tm1Clar
Targeted Allele Detail

Summary

• Symbol: Slc6a8^tm1Clar
• Name: solute carrier family 6 (neurotransmitter transporter, creatine), member 8; targeted mutation 1, Joseph Clark
• MGI ID: MGI:4941754
• Gene: Slc6a8 Location: ChrX:72716756-72726108 bp, + strand Genetic Position: ChrX, 37.38 cM
• Alliance: Slc6a8^tm1Clar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169472
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. (J:169472)

Generation of the Slc6a8^tm1Clar, Slc6a8^tm1.1Clar, and Slc6a8^tm1.2Clar alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a8 Mutation: 10 strains or lines available

References

• Original: J:169472 Skelton MR, et al., Creatine transporter (CrT; Slc6a8) knockout mice as a model of human CrT deficiency. PLoS One. 2011;6(1):e16187
• All: 2 reference(s)