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Tg(Thy1-QPCT)#Tbay
Transgene Detail
Nomenclature
Symbol: Tg(Thy1-QPCT)#Tbay
Name: transgene insertion, Thomas A Bayer
MGI ID: MGI:4941713
Synonyms: hQC
Transgene: Tg(Thy1-QPCT)#Tbay  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J x CBA
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse promoter is used to drive the human cDNA. No line snames or symbols were provided. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:169481)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:169481 Jawhar S, et al., Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice. J Biol Chem. 2011 Feb 11;286(6):4454-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory