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Transgene Detail
Symbol: Tg(Mt1-CETP)#Tall
Name: transgene insertion, Alan Tall
MGI ID: MGI:4941577
Transgene: Tg(Mt1-CETP)#Tall  Location: unknown  
Strain of Origin:  (C57BL/6J x CBA/J)F1
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsA 5' genomic region of the human CETP including 138 base pairs of flanking sequence, exon1, intron 1 and part of exon 2 was linked using a fragment of human CETP cDNA to a 3' sequence of the same gene made up of part of exon 13, exons 14-16, introns 13-15, and 121 base pairs of flanking sequence. The resulting construct lacks introns 2-12. One male and one female founder were identified but a line was established only from the female founder. Only one copy of the transgene was inserted. (J:93800)
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:93800 Agellon LB, et al., Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice. J Biol Chem. 1991 Jun 15;266(17):10796-801
All:  5 reference(s)

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MGI 6.04
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