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Lamc3tm1.1Wjbr
Targeted Allele Detail
Nomenclature
Symbol: Lamc3tm1.1Wjbr
Name: laminin gamma 3; targeted mutation 1.1, William J Brunken
MGI ID: MGI:4941480
Synonyms: Lamc3tm1Wjbr
Gene: Lamc3  Location: Chr2:31887291-31946539 bp, + strand  Genetic Position: Chr2, 21.93 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169656
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 2.2 kb fragment spanning exon 1 and part of intron 1 was replaced with an IRES betageo cassette via homologous recombination. The neo selection cassette was removed by mating the heterozygous mouse with a sperm-Cre expressing mouse. (J:169656, J:184380)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lamc3 Mutation:  3 strains or lines available
References
Original:  J:169656 Denes V, et al., Laminin deficits induce alterations in the development of dopaminergic neurons in the mouse retina. Vis Neurosci. 2007 Jul-Aug;24(4):549-62
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory