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Atp1a4tm1Itl
Targeted Allele Detail
Nomenclature
Symbol: Atp1a4tm1Itl
Name: ATPase, Na+/K+ transporting, alpha 4 polypeptide; targeted mutation 1, inGenious Targeting Laboratory
MGI ID: MGI:4941050
Synonyms: Atp1a4tm1Igl
Gene: Atp1a4  Location: Chr1:172223513-172258414 bp, - strand  Genetic Position: Chr1, 79.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169420
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 5 through 8 were replaced with a neo cassette. Sperm lack sodium-potassium ATPase activity. (J:169420)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atp1a4 Mutation:  29 strains or lines available
References
Original:  J:169420 Jimenez T, et al., Na,K-ATPase alpha4 isoform is essential for sperm fertility. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):644-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory