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Targeted Allele Detail
Symbol: Hand2tm2.1Dsr
Name: heart and neural crest derivatives expressed transcript 2; targeted mutation 2.1, Deepak Srivastava
MGI ID: MGI:4940061
Synonyms: Hand2loxp
Gene: Hand2  Location: Chr8:57320983-57324517 bp, + strand  Genetic Position: Chr8, 29.8 cM
Germline Transmission:  Earliest citation of germline transmission: J:169213
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette. (J:169213)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hand2 Mutation:  1 strain or line available
Original:  J:169213 Tsuchihashi T, et al., Hand2 function in second heart field progenitors is essential for cardiogenesis. Dev Biol. 2011 Mar 1;351(1):62-69
All:  3 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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