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Mycbp2tm1.1Klsc
Targeted Allele Detail
Nomenclature
Symbol: Mycbp2tm1.1Klsc
Name: MYC binding protein 2, E3 ubiquitin protein ligase; targeted mutation 1.1, Klaus Scholich
MGI ID: MGI:4939601
Synonyms: MYCBP2lox
Gene: Mycbp2  Location: Chr14:103113411-103346800 bp, - strand  Genetic Position: Chr14, 51.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168745
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 11 was floxed. An FRT-flanked neo cassette was removed by flp-mediated recombination. (J:168745)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mycbp2 Mutation:  151 strains or lines available
References
Original:  J:168745 Holland S, et al., The Ubiquitin Ligase MYCBP2 Regulates Transient Receptor Potential Vanilloid Receptor 1 (TRPV1) Internalization through Inhibition of p38 MAPK Signaling. J Biol Chem. 2011 Feb 4;286(5):3671-80
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory