Gphn^tm1Trill
Targeted Allele Detail

Summary

• Symbol: Gphn^tm1Trill
• Name: gephyrin; targeted mutation 1, Antoine Triller
• MGI ID: MGI:4888559
• Synonyms: C2mRFP.Ge, gephryin-mRFP
• Gene: Gphn Location: Chr12:78273153-78731546 bp, + strand Genetic Position: Chr12, 35.51 cM, cytoband D2
• Alliance: Gphn^tm1Trill page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167979
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A T7-mRFP with a consensus TEV cleavage sequence was inserted into exon 3. The cassette remained maintained under the control of the endogenous gephyrin promoter. (J:167979)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gphn Mutation: 88 strains or lines available

References

• Original: J:167979 Machado P, et al., Heat shock cognate protein 70 regulates gephyrin clustering. J Neurosci. 2011 Jan 5;31(1):3-14
• All: 3 reference(s)