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Sfntm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Sfntm1Mak
Name: stratifin; targeted mutation 1, Tak Mak
MGI ID: MGI:4888527
Gene: Sfn  Location: Chr4:133600556-133602168 bp, - strand  Genetic Position: Chr4, 66.25 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168328
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted into the coding exon. The absence of protein expression was confirmed by western blot analysis on intestinal epithelial cell extracts. (J:168328)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sfn Mutation:  6 strains or lines available
References
Original:  J:168328 Su YW, et al., 14-3-3{sigma} regulates B-cell homeostasis through stabilization of FOXO1. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1555-60
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory