About   Help   FAQ
Slco2a1tm1.2Vsch
Targeted Allele Detail
Nomenclature
Symbol: Slco2a1tm1.2Vsch
Name: solute carrier organic anion transporter family, member 2a1; targeted mutation 1.2, Victor L Schuster
MGI ID: MGI:4888397
Gene: Slco2a1  Location: Chr9:102988712-103096002 bp, + strand  Genetic Position: Chr9, 54.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168442
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Flp- and cre-mediated recombination remove the neo cassette and exon 1, respectively. The absence of protein expression was confirmed by immunohistochemistry. (J:168442)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slco2a1 Mutation:  25 strains or lines available
References
Original:  J:168442 Chang HY, et al., Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice. Circulation. 2010 Feb 2;121(4):529-36
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/10/2017
MGI 6.10
The Jackson Laboratory