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Slco2a1tm1.2Vsch
Targeted Allele Detail
Nomenclature
Symbol: Slco2a1tm1.2Vsch
Name: solute carrier organic anion transporter family, member 2a1; targeted mutation 1.2, Victor L Schuster
MGI ID: MGI:4888397
Gene: Slco2a1  Location: Chr9:102988712-103096002 bp, + strand  Genetic Position: Chr9, 54.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168442
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Flp- and cre-mediated recombination remove the neo cassette and exon 1, respectively. The absence of protein expression was confirmed by immunohistochemistry. (J:168442)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slco2a1 Mutation:  18 strains or lines available
References
Original:  J:168442 Chang HY, et al., Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice. Circulation. 2010 Feb 2;121(4):529-36
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory