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Il2rgtm1.1Flv
Targeted Allele Detail
Nomenclature
Symbol: Il2rgtm1.1Flv
Name: interleukin 2 receptor, gamma chain; targeted mutation 1.1, Richard A Flavell
MGI ID: MGI:4887837
Gene: Il2rg  Location: ChrX:101264378-101268255 bp, - strand  Genetic Position: ChrX, 43.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168303
Parent Cell Line:  V17 (ES Cell)
Strain of Origin:  BALB/cAnNTac x 129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA floxed human ubiquitin promoter-driven hygromycin cassette replaced the coding region. Cre-mediated recombination removed the hygro cassette. (J:168303)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Il2rg Mutation:  70 strains or lines available
Notes
Originally generated in conjunction with Rag2tm1.1Flv.
References
Original:  J:168303 Song J, et al., A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe. 2010 Oct 21;8(4):369-76
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory