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Rag2tm1.1Flv
Targeted Allele Detail
Nomenclature
Symbol: Rag2tm1.1Flv
Name: recombination activating gene 2; targeted mutation 1.1, Richard A Flavell
MGI ID: MGI:4887836
Gene: Rag2  Location: Chr2:101624718-101632529 bp, + strand  Genetic Position: Chr2, 53.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:168303
Parent Cell Line:  V17 (ES Cell)
Strain of Origin:  BALB/cAnNTac x 129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA floxed PGK-neomycin cassette replaced the coding region. Cre-mediated recombination removed the neo cassette. (J:168303)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 7 strains available      Cell Lines: 0 lines available
Carrying any Rag2 Mutation:  47 strains or lines available
Notes
Originally generated in conjunction with Il2rgtm1.1Flv.

References
Original:  J:168303 Song J, et al., A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe. 2010 Oct 21;8(4):369-76
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory