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Wlstm1.2Whsu
Targeted Allele Detail
Nomenclature
Symbol: Wlstm1.2Whsu
Name: wntless WNT ligand secretion mediator; targeted mutation 1.2, Wei Hsu
MGI ID: MGI:4881719
Synonyms: Gpr177delta
Gene: Wls  Location: Chr3:159839672-159938664 bp, + strand  Genetic Position: Chr3, 82.65 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167835
Parent Cell Line:  CSL3 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed exon 3 and the neo cassette. (J:167835)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wls Mutation:  8 strains or lines available
References
Original:  J:167835 Fu J, et al., Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn. 2011 Feb;240(2):365-71
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory