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Tg(Trpv1-icre)1Kldr
Transgene Detail
Nomenclature
Symbol: Tg(Trpv1-icre)1Kldr
Name: transgene insertion 1, Klas Kullander
MGI ID: MGI:4880764
Synonyms: TRPV1-Cre
Transgene: Tg(Trpv1-icre)1Kldr  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA cassette containing codon improved cre (icre) and an FRT-flanked ampicillin resistance gene was inserted at the ATG site in the first exon in the Trpv1 gene in BAC RP23-292B23 containing the entire Trpv1 locus. The ampicillin gene was removed from the BAC construct by Flp expression. The purified BAC was microinjected into pronuclei of mouse oocytes. (J:167752)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trpv1     Summary of all recombinase alleles driven by Trpv1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:167752 Lagerstrom MC, et al., VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch. Neuron. 2010 Nov 4;68(3):529-42
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory