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Targeted Allele Detail
Symbol: Ripply3tm1Sjt
Name: ripply3 homolog (zebrafish); targeted mutation 1, Shinji Takada
MGI ID: MGI:4880754
Gene: Ripply3  Location: Chr16:94328420-94336935 bp, + strand  Genetic Position: Chr16, 55.17 cM, cytoband C4
Germline Transmission:  Earliest citation of germline transmission: J:167713
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 1 - 3 were replaced with an IRES-lacZ-pgk-neo cassette via homologous recombination. RT-PCR analysis confirmed the absence of expression in homozygous embryos at E9.5. (J:167713)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ripply3 Mutation:  3 strains or lines available
Original:  J:167713 Okubo T, et al., Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice. Development. 2011 Jan;138(2):339-48
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory