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Mdga1tm1.1Tymo
Targeted Allele Detail
Summary
Symbol: Mdga1tm1.1Tymo
Name: MAM domain containing glycosylphosphatidylinositol anchor 1; targeted mutation 1.1, Toru Yamamoto
MGI ID: MGI:4878863
Synonyms: Mdga1LacZ
Gene: Mdga1  Location: Chr17:30046930-30107557 bp, - strand  Genetic Position: Chr17, 15.54 cM, cytoband B1
Alliance: Mdga1tm1.1Tymo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166980
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a lacZ and FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette. The absence of protein expression was confirmed by western blot analysis on E15.5 and P14 brain extracts. (J:166980)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 131 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Mdga1 Mutation:  78 strains or lines available
References
Original:  J:166980 Ishikawa T, et al., IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Dev Dyn. 2011 Jan;240(1):96-107
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory