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Ptbp1tm1Msol
Targeted Allele Detail
Nomenclature
Symbol: Ptbp1tm1Msol
Name: polypyrimidine tract binding protein 1; targeted mutation 1, Michele Solimena
MGI ID: MGI:4868473
Synonyms: PTBP1loxP
Gene: Ptbp1  Location: Chr10:79854432-79864435 bp, + strand  Genetic Position: Chr10, 39.72 cM
Small size of Ptbp1tm1Msol/Ptbp1tm1Msol embryos

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166852
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (No functional change, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA cassette containing an FRT site, splice acceptor, IRES, lacZ gene, hygromycin resistance, STOP sequence, FRT site and loxP site was inserted upstream of exon 3. An additional loxP site was inserted upstream of exon 7. (J:223915)
Generation of the Ptbp1tm1Msol allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptbp1 Mutation:  16 strains or lines available
References
Original:  J:166852 Liu Y, et al., Tamoxifen-independent recombination in the RIP-CreER mouse. PLoS One. 2010;5(10):e13533
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory