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Mmp15tm1Kohl
Targeted Allele Detail
Nomenclature
Symbol: Mmp15tm1Kohl
Name: matrix metallopeptidase 15; targeted mutation 1, Kenn Holmbeck
MGI ID: MGI:4868411
Gene: Mmp15  Location: Chr8:95352268-95374293 bp, + strand  Genetic Position: Chr8, 47.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:167396
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 2 through exon 5 was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on embryo extracts. (J:167396)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mmp15 Mutation:  2 strains or lines available
References
Original:  J:167396 Szabova L, et al., Membrane-type MMPs are indispensable for placental labyrinth formation and development. Blood. 2010 Dec 16;116(25):5752-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory