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Myo9btm1.2Bah
Targeted Allele Detail
Nomenclature
Symbol: Myo9btm1.2Bah
Name: myosin IXb; targeted mutation 1.2, Martin Bahler
MGI ID: MGI:4867915
Synonyms: Myo9b-, Myo9b TypeI
Gene: Myo9b  Location: Chr8:71272714-71360713 bp, + strand  Genetic Position: Chr8, 34.43 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:162326
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 2 was removed by crossing Myo9btm1.1Bah mice with ZAP3-Cre-recombinase transgenic mice. Absence of protein was confirmed by western blot in spleen, thymus, and isolated immune cells. This is a null allele. (J:162326)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myo9b Mutation:  63 strains or lines available
References
Original:  J:162326 Hanley PJ, et al., Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12145-50
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory