Myo9b^tm1.1Bah
Targeted Allele Detail

Summary

• Symbol: Myo9b^tm1.1Bah
• Name: myosin IXb; targeted mutation 1.1, Martin Bahler
• MGI ID: MGI:4867913
• Synonyms: Myo9b floxed, Myo9b TypeII
• Gene: Myo9b Location: Chr8:71725358-71813357 bp, + strand Genetic Position: Chr8, 34.43 cM
• Alliance: Myo9b^tm1.1Bah page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:162326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: Two loxP sites flanking exon 2 and a neomycin-resistance gene flanked by flippase recognition sites following it are inserted by targeted homologous recombination. The neomycin cassette was removed by crossing chimeric mice with Flippase transgenic mice. This is a conditional allele. (J:162326)

Generation of the Myo9b^tm1.1Bah and Myo9b^tm1.2Bah alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo9b Mutation: 107 strains or lines available

References

• Original: J:162326 Hanley PJ, et al., Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility. Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12145-50
• All: 1 reference(s)