Lsamp^tm1Jinn
Targeted Allele Detail

Summary

• Symbol: Lsamp^tm1Jinn
• Name: limbic system-associated membrane protein; targeted mutation 1, Jurgen Innos
• MGI ID: MGI:4867852
• Gene: Lsamp Location: Chr16:39804723-42002042 bp, + strand Genetic Position: Chr16, 28.26 cM, cytoband B5
• Alliance: Lsamp^tm1Jinn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166944
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1b was replaced with a lacZ and neo cassette. The absence of expression was confirmed by western blot analysis on frontal cortex, midbrain, kidney, and liver extracts. (J:166944)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lsamp Mutation: 25 strains or lines available

References

• Original: J:166944 Innos J, et al., Lower anxiety and a decrease in agonistic behaviour in Lsamp-deficient mice. Behav Brain Res. 2011 Feb 2;217(1):21-31
• All: 7 reference(s)