T^M1Shao
Spontaneous Allele Detail

Summary

• Symbol: T^M1Shao
• Name: brachyury, T-box transcription factor T; mutation 1, Yixiang Shao
• MGI ID: MGI:4867537
• Synonyms: T^Shao
• Gene: T Location: Chr17:8653255-8661328 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: T^M1Shao page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous T-to-A transversion in the 66th nucleotide of exon 2 results in a splicing error that excludes the first 67 nucleotides of exon 2 from the transcript, causing a frameshift and early termination of translation. (J:166619)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any T Mutation: 60 strains or lines available

References

• Original: J:166619 Wu B, et al., Identification of a novel mouse brachyury (T) allele causing a short tail mutation in mice. Cell Biochem Biophys. 2010 Dec;58(3):129-35
• All: 1 reference(s)