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Scttm1.1Bkcc
Targeted Allele Detail
Nomenclature
Symbol: Scttm1.1Bkcc
Name: secretin; targeted mutation 1.1, Billy K C Chow
MGI ID: MGI:4847670
Gene: Sct  Location: Chr7:141278330-141279133 bp, - strand  Genetic Position: Chr7, 86.59 cM, cytoband F5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166370
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1, and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 1 through 4. (J:166370)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sct Mutation:  5 strains or lines available
References
Original:  J:166370 Lee VH, et al., An indispensable role of secretin in mediating the osmoregulatory functions of angiotensin II. FASEB J. 2010 Dec;24(12):5024-32
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory