About   Help   FAQ
Ackr4tm1.1Rjbn
Targeted Allele Detail
Nomenclature
Symbol: Ackr4tm1.1Rjbn
Name: atypical chemokine receptor 4; targeted mutation 1.1, Robert J B Nibbs
MGI ID: MGI:4847614
Synonyms: CCRL1-
Gene: Ackr4  Location: Chr9:104084157-104126933 bp, - strand  Genetic Position: Chr9, 56.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:166490
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. The absence of transcript expression was confirmed by RT-PCR on thymus and heart extracts. (J:166490)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ackr4 Mutation:  15 strains or lines available
References
Original:  J:166490 Comerford I, et al., The atypical chemokine receptor CCX-CKR scavenges homeostatic chemokines in circulation and tissues and suppresses Th17 responses. Blood. 2010 Nov 18;116(20):4130-40
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/18/2017
MGI 6.08
The Jackson Laboratory