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Targeted Allele Detail
Symbol: Ackr4tm1.1Rjbn
Name: atypical chemokine receptor 4; targeted mutation 1.1, Robert J B Nibbs
MGI ID: MGI:4847614
Synonyms: CCRL1-
Gene: Ackr4  Location: Chr9:104084157-104126933 bp, - strand  Genetic Position: Chr9, 56.47 cM
Germline Transmission:  Earliest citation of germline transmission: J:166490
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 4 was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. The absence of transcript expression was confirmed by RT-PCR on thymus and heart extracts. (J:166490)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ackr4 Mutation:  19 strains or lines available
Original:  J:166490 Comerford I, et al., The atypical chemokine receptor CCX-CKR scavenges homeostatic chemokines in circulation and tissues and suppresses Th17 responses. Blood. 2010 Nov 18;116(20):4130-40
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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