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Pkd2tm1.2Tjwt
Targeted Allele Detail
Summary
Symbol: Pkd2tm1.2Tjwt
Name: polycystin 2, transient receptor potential cation channel; targeted mutation 1.2, Terry J Watnick
MGI ID: MGI:4843127
Synonyms: Pkd2delta11-13
Gene: Pkd2  Location: Chr5:104607316-104653685 bp, + strand  Genetic Position: Chr5, 50.68 cM
Alliance: Pkd2tm1.2Tjwt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165114
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exons 11 through 13 from Pkd2tm1.1Tjwt. The absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:165114)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pkd2 Mutation:  84 strains or lines available
References
Original:  J:165114 Garcia-Gonzalez MA, et al., Pkd1 and Pkd2 are required for normal placental development. PLoS One. 2010;5(9)
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory