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Plcg2Ali14
Chemically induced Allele Detail
Nomenclature
Symbol: Plcg2Ali14
Name: phospholipase C, gamma 2; Abnormal limb 14
MGI ID: MGI:4840229
Gene: Plcg2  Location: Chr8:117498291-117635142 bp, + strand  Genetic Position: Chr8, 64.26 cM
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsIdentified as part of a dominant dysmorphology screen of ENU induced mutations. Tyrosine 495 in the spPH domain is replaced by Cysteine. (J:166106)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plcg2 Mutation:  25 strains or lines available
References
Original:  J:166106 Everett KL, et al., Characterization of phospholipase C gamma enzymes with gain-of-function mutations. J Biol Chem. 2009 Aug 21;284(34):23083-93
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory