Kitl^M1Bao
Chemically induced Allele Detail

Summary

• Symbol: Kitl^M1Bao
• Name: kit ligand; mutation 1, Baojin Wu
• MGI ID: MGI:4839549
• Synonyms: Kitl^1-bao, Kitl^-1Bao
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^M1Bao page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This ENU induced mutation has a GT to GC transition at the splicing donor site of intron 8, which results in the deletion of exon 8 and a frameshift, although there are some normal splicing forms in the brain. (J:163981)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 92 strains or lines available

References

• Original: J:163981 Xue ZF, et al., A mutation in the eighth intron of the kit1 gene leads to abnormal mRNA splicing in mice. Acta Zooligica Sinica. 2007;53(2):332-338
• All: 2 reference(s)