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Tg(Sox3)1Pqt
Transgene Detail
Nomenclature
Symbol: Tg(Sox3)1Pqt
Name: transgene insertion 1, Paul Q Thomas
MGI ID: MGI:4839388
Synonyms: Sox3 transgene sex reversed, SR, Tg(Sox3-EGFP)SrPqt
Transgene: Tg(Sox3)1Pqt  Location: unknown  Genetic Position: Chr19, Syntenic
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(Sox3)1Pqt expresses 1 gene
 
Mutation detailsTwo copies of the transgene, comprising approximately 36 kb of genomic sequence from the Sox3 locus followed by an internal ribosomal entry site (IRES) and a cDNA encoding enhanced green fluorescent protein (EGFP), have integrated into Chr 19 at bands B/C1, upstream of the aldehyde dehydrogenase superfamily 1, subfamily A1 gene. (J:171839)
Inheritance:    Not Specified
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:171839 Sutton E, et al., Identification of SOX3 as an XX male sex reversal gene in mice and humans. J Clin Invest. 2011 Jan 4;121(1):328-41
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/13/2015
MGI 5.21
The Jackson Laboratory