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Rapgef2tm1.2Hous
Targeted Allele Detail
Nomenclature
Symbol: Rapgef2tm1.2Hous
Name: Rap guanine nucleotide exchange factor (GEF) 2; targeted mutation 1.2, Steven X Hou
MGI ID: MGI:4839129
Gene: Rapgef2  Location: Chr3:79062516-79286517 bp, - strand  Genetic Position: Chr3, 34.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165879
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 18. The absence of transcript expression was confirmed by northern blot analysis and in situ hydridization of E10.5 embryos. (J:165879)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rapgef2 Mutation:  32 strains or lines available
References
Original:  J:165879 Satyanarayana A, et al., RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. Blood. 2010 Oct 21;116(16):2921-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory