About   Help   FAQ
Rapgef2tm1.2Hous
Targeted Allele Detail
Nomenclature
Symbol: Rapgef2tm1.2Hous
Name: Rap guanine nucleotide exchange factor (GEF) 2; targeted mutation 1.2, Steven X Hou
MGI ID: MGI:4839129
Gene: Rapgef2  Location: Chr3:79062516-79286517 bp, - strand  Genetic Position: Chr3, 34.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165879
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 18. The absence of transcript expression was confirmed by northern blot analysis and in situ hydridization of E10.5 embryos. (J:165879)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rapgef2 Mutation:  38 strains or lines available
References
Original:  J:165879 Satyanarayana A, et al., RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. Blood. 2010 Oct 21;116(16):2921-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory