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Fbn1tm1.2Lysa
Targeted Allele Detail
Nomenclature
Symbol: Fbn1tm1.2Lysa
Name: fibrillin 1; targeted mutation 1.2, Lynn Y Sakai
MGI ID: MGI:4839045
Synonyms: GT8
Gene: Fbn1  Location: Chr2:125300594-125507993 bp, - strand  Genetic Position: Chr2, 61.38 cM, cytoband F
Fragmentation of aortic root elastic lamellae in Fbn1tm1.2Lysa/Fbn1+ mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165897
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Inversion
 
Mutation details
Generation of the Fbn1tm1.2Lysa allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fbn1 Mutation:  6 strains or lines available
References
Original:  J:165897 Charbonneau NL, et al., In vivo studies of mutant fibrillin-1 microfibrils. J Biol Chem. 2010 Aug 6;285(32):24943-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory