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Clec1btm1.1Ksi
Targeted Allele Detail
Nomenclature
Symbol: Clec1btm1.1Ksi
Name: C-type lectin domain family 1, member b; targeted mutation 1.1, Katsue Suzuki-Inoue
MGI ID: MGI:4839037
Gene: Clec1b  Location: Chr6:129397297-129409335 bp, + strand  Genetic Position: Chr6, 63.3 cM, cytoband F3
Lymphatic function is impaired in Clec1btm1.1Ksi/Clec1btm1.1Ksi embryos

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165898
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre mediated recombination removed part of exon 1 while leaving the neo cassette intact. (J:165898)
Generation of the Clec1btm1Ksi and Clec1btm1.1Ksi alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clec1b Mutation:  6 strains or lines available
References
Original:  J:165898 Suzuki-Inoue K, et al., Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J Biol Chem. 2010 Aug 6;285(32):24494-507
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory