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Elmo1tm1.2Ravi
Targeted Allele Detail
Nomenclature
Symbol: Elmo1tm1.2Ravi
Name: engulfment and cell motility 1; targeted mutation 1.2, Kodi S Ravichandran
MGI ID: MGI:4838428
Synonyms: Elmo1-, Elmo1delta5
Gene: Elmo1  Location: Chr13:20090596-20608353 bp, + strand  Genetic Position: Chr13, 7.21 cM, cytoband A3.1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:164662
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre mediated recombination removed exon 5. The absence of protein expression was confirmed by western blot analysis on bone marrow-derived macrophage. (J:164662)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Elmo1 Mutation:  13 strains or lines available
References
Original:  J:164662 Elliott MR, et al., Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo. Nature. 2010 Sep 16;467(7313):333-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory