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Cdc20tm1Jvd
Targeted Allele Detail
Nomenclature
Symbol: Cdc20tm1Jvd
Name: cell division cycle 20; targeted mutation 1, Jan M A van Deursen
MGI ID: MGI:4838294
Synonyms: Cdc20H
Gene: Cdc20  Location: Chr4:118432901-118437352 bp, - strand  Genetic Position: Chr4, 54.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165500
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Hypomorph)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette with stop codons in all three frames was inserted between exon 3 and 4. Reduced protein expression was confirmed by western blot analysis on testes and ovary extracts. This allele is hypomorphic. (J:165500)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdc20 Mutation:  14 strains or lines available
References
Original:  J:165500 Jin F, et al., Cdc20 is critical for meiosis I and fertility of female mice. PLoS Genet. 2010;6(9)
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory