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Cd226tm1Shib
Targeted Allele Detail
Nomenclature
Symbol: Cd226tm1Shib
Name: CD226 antigen; targeted mutation 1, Akira Shibuya
MGI ID: MGI:4838287
Gene: Cd226  Location: Chr18:89197431-89270201 bp, + strand  Genetic Position: Chr18, 59.05 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165704
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neo cassette. Flow cytometry confirmed the absence of spleen cells expressing the protein. (J:165704)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd226 Mutation:  18 strains or lines available
References
Original:  J:165704 Iguchi-Manaka A, et al., Accelerated tumor growth in mice deficient in DNAM-1 receptor. J Exp Med. 2008 Dec 22;205(13):2959-64
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory