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Rbfox2tm1.1Dblk
Targeted Allele Detail
Summary
Symbol: Rbfox2tm1.1Dblk
Name: RNA binding protein, fox-1 homolog (C. elegans) 2; targeted mutation 1.1, Douglas Black
MGI ID: MGI:4838182
Synonyms: Fox-2flox, Rbfox2loxP
Gene: Rbfox2  Location: Chr15:76963190-77191204 bp, - strand  Genetic Position: Chr15, 36.4 cM, cytoband E1
Alliance: Rbfox2tm1.1Dblk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:165699
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert loxP sites flanking exons 6-7 of the RNA binding protein, fox-1 homolog 2 (Rbfox2) gene, followed by a FRT-flanked neomycin resistance (neo) cassette. Flp-mediated recombination removed the neo cassette and left exons 6 and 7 floxed. (J:165699)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 23 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rbfox2 Mutation:  79 strains or lines available
References
Original:  J:165699 Black D, Direct Data Submission 2010/11/09. MGI Direct Data Submission. 2010;
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory